In the field of safe and flexible operation of industrial plants and machines, the M2Smart®HMI5 is the optimal, mobile solution. Where stationary or wired operating systems had to be used in the past, the M2Smart® HMI5 with the associated safety components offers completely new possibilities. Via a “functionally safe” radio connection, it is possible for the first time to meet the requirements of, for example, the Machinery Directive in terms of safety equipment of a machine even with a wireless operating system. Both the emergency stop button, which is obligatory in this environment, and a three-stage enabling switch are located directly on the handheld and the corresponding signals, packaged in an encrypted “data packet”, are transmitted via Bluetooth to the M2Smart® Gateway, which takes over the transfer of the data to the machine. A major focus here is on the usability of the system.